Schalch Lab

Selected Papers [ Show all publications ]

2017

2016

SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.
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Mol Cell, ; 62 (2): 207-221

2015

Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing.
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Mol Cell Biol, ; 35 (4): 662-674

2014

CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing.
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Proc Natl Acad Sci U S A, ; 111 (5): 1795-1800

2011

The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS.
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Nat Struct Mol Biol, ; 18 (12): 1351-1357

2009

High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin.
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Mol Cell, ; 34 (1): 36-46

2006

The molecular architecture of the metalloprotease FtsH.
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Proc Natl Acad Sci U S A, ; 103 (9): 3066-3071

2005

X-ray structure of a tetranucleosome and its implications for the chromatin fibre.
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Nature, ; 436 (7047): 138-141

2004

Nucleosome arrays reveal the two-start organization of the chromatin fiber.
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Science, ; 306 (5701): 1571-1573

2003

Chromatin fiber folding: requirement for the histone H4 N-terminal tail.
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J Mol Biol, ; 327 (1): 85-96