Thore Lab

Selected Papers [ Show all publications ]

2015

Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells.
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Cell Rep, ; 12 (4): 554-561
Polyuridylation in Eukaryotes: A 3'-End Modification Regulating RNA Life.
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Biomed Res Int, ; 2015 968127

2014

An artificial PPR scaffold for programmable RNA recognition.
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Nat Commun, ; 5 5729
The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.
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Nucleic Acids Res, ; 42 (10): 6742-6752
A critical switch in the enzymatic properties of the Cid1 protein deciphered from its product-bound crystal structure.
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Nucleic Acids Res, ; 42 (5): 3372-3380
Steroid receptor RNA activator (SRA) modification by the human pseudouridine synthase 1 (hPus1p): RNA binding, activity, and atomic model.
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PLoS One, ; 9 (4): e94610

2012

Functional implications from the Cid1 poly(U) polymerase crystal structure.
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Structure, ; 20 (6): 977-986
Structural basis of transcriptional gene silencing mediated by Arabidopsis MOM1.
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PLoS Genet, ; 8 (2): e1002484

2010

Expression, crystallization and preliminary X-ray diffraction analysis of the CMM2 region of the Arabidopsis thaliana Morpheus' molecule 1 protein.
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Acta Crystallogr Sect F Struct Biol Cryst Commun, ; 66 (Pt 8): 916-918

2008

Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch.
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J Am Chem Soc, ; 130 (26): 8116-8117

2006

Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand.
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Science, ; 312 (5777): 1208-1211

2003

X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex.
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EMBO Rep, ; 4 (12): 1150-1155
Crystal structures of the Pyrococcus abyssi Sm core and its complex with RNA. Common features of RNA binding in archaea and eukarya.
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J Biol Chem, ; 278 (2): 1239-1247