Département de biologie moléculaire
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Open Positions

PhD and postdoctoral positions in RNA biology

Department of Molecular Biology, University of Geneva, Switzerland

The Pillai laboratory is seeking to recruit one PhD student and two postdoctoral fellows to study the role of RNA modifications in gene expression control.

RNA molecules can be modified by over 150 different chemical marks and their importance in gene regulation is being rapidly uncovered. The N6-methyladenosine (m6A) mark is an abundant internal modification on RNAs and this is highly conserved from yeast to plants and animals. RNA methytransferases "write" this mark on transcripts, and this can be "erased" by demethylases, making it a dynamic regulatory modification. Proteins that can recognise the mark "read" the signal on messages to impact RNA stability, translation, splicing and export.

This interdisciplinary project will also make use of mouse models, protein biochemistry, cell biology and computer methods.

Candidates with prior experience in working with RNA, protein biochemistry, structural biology, mouse genetics or computational biology are invited to apply.

Apply with a brief motivation letter (~300 words) and a CV to : ramesh.pillai@unige.ch

Date Posted: Feb 5, 2019, 9:41 AM

PhD Student and Postdoctoral Positions

PhD Student and Postdoctoral positions are available to work on a project on oncogene-induced DNA replication stress that is being funded by an ERC Advanced Investigator Grant (REPLISTRESS; October 2018-September 2023). The goals of the project are to understand the mechanisms by which oncogenes induce DNA replication stress and to identify the key pathways, whose inhibition leads to synthetic lethality in cells that have oncogene-induced DNA replication stress. The methodology employed utilizes high throughput sequencing to examine nascent DNA replication, transcription and patterns of genomic instability.

Interested candidates can send their CV, unofficial grades from their Bachelor studies and short motivation letter to Thanos Halazonetis

Date Posted: Dec 6, 2018, 3:39 PM

PhD Student and Postdoctoral Positions

Positions are available for talented and highly motivated candidates at the PhD or Post Doc level. Projects involve dissecting the structure, function and regulation of TOR Complexes using structure biology, molecular biology and biophysical approaches including advanced microscopy. Mass spectrometry or electron microscopy or yeast molecular biology experience would also be an asset.

Interested candidates can send their CV and short motivation letter to Robbie Loewith

Date Posted: Dec 21, 2015, 9:16 AM